Kyle Lowry added 26 points and 10 assists, and Serge Ibaka had 13 points and 13 rebounds for the Raptors, who won at Phoenix on Tuesday night to end a three-game losing streak.
Murray had 18 points, and Nikola Jokic added 14 points, 11 rebounds and eight assists.
Shake Milton scored 20 points and Al Horford had 18 points, eight rebounds and six assists for the Sixers, who also won in Sacramento for the first time since 2015. Alec Burks added 17 points and Raul Neto had 16.
De’Aaron Fox had 23 points and seven assists for Sacramento.